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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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Recombinant mouse CCL4 (C-C motif chemokine ligand 4) is a proinflammatory chemokine expressed in E. coli and supplied lyophilized for research use. It promotes leukocyte chemotaxis, acts as a monokine that can form homodimers, and is provided with high purity suitable for in vitro studies of inflammation and immune cell migration.
High purity (>95%) as determined by reducing SDS-PAGE.
Recombinant expression in E. coli without affinity tag.
Supplied lyophilized from buffered formulation for stability.
Predicted molecular mass ~7.8 kDa (observed ~5-10 kDa by SDS-PAGE).
Intended for in vitro research applications studying chemotaxis and inflammation.
Stable when aliquoted and stored at -20°C or -80°C for extended storage.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
CB-6644 is a selective allosteric inhibitor of the RUVBL1/2 ATPase with a reported IC50 of 15 nM. It exhibits antiproliferative activity in multiple cancer cell lines and oral antitumor efficacy in xenograft models.
Selective inhibitor of the RUVBL1/2 complex
Blocks ATPase activity with an IC50 of 15 nM
Demonstrates antiproliferative activity in vitro
Shows oral antitumor efficacy in xenograft models
Solid, white to light yellow appearance
Soluble in DMSO (100 mg/mL); in vivo formulations reported at ≥ 2.08 mg/mL
Store solid at -20°C under nitrogen; solutions at -80°C for long-term storage
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CCL4 Protein Human is a small cytokine of the CC chemokine subfamily that binds to the CCR5 chemokine receptor on the cell surface promotes leukocyte aggregation under various inflammatory conditions and contributes to immune protection against human immunodeficiency virus type 1 CCL4 Protein Human is a recombinant human CCL4 (A24-N92) expressed by E coli[1]
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Omzotirome is a synthetic thyromimetic research compound used to study lipid metabolism and metabolic regulation. Reported preclinical data show it increases energy expenditure and fatty acid oxidation and reduces adiposity in high-fat diet rodent models, making it a tool compound for hyperlipidaemia and metabolic research.
Functional analog of iodothyronines.
Reported to increase energy expenditure in rodent studies.
Enhances fatty acid oxidation in preclinical models.
Suitable for hyperlipidaemia and metabolic research applications.
High purity (≥99.9%) appropriate for biochemical assays.
Chemical identifiers: CAS 1092551-88-6; molecular weight 328.41 g/mol; formula C19H24N2O3.
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TEPC466 is an aggregation-induced emission (AIE) fluorescent probe based on TEPP-46, designed for selective detection and imaging of pyruvate kinase M2 (PKM2) in biological samples. It is used for cellular imaging applications and is supplied as a high-purity research chemical.
Selective detection of PKM2 via the AIE effect.
Suitable for cellular imaging applications.
High purity (99.43%) for reliable experimental results.
Molecular weight 544.6 g/mol; formula C27H20N4O5S2.
Multiple pack sizes available for experimental flexibility.
Accompanied by analytical documents such as COA, HNMR, LCMS, and RP-HPLC.
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